Generalized anxiety disorder: comorbidity, comparative biology and treatment

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Generalized anxiety disorder: comorbidity, comparative biology and treatment.

Generalized anxiety disorder (GAD) is a severe and chronic anxiety disorder characterized by uncontrollable worrying and somatic anxiety (tension, insomnia and hypervigilance). It is a common condition, with lifetime prevalence rates for DSM-IV GAD in the general population of approx. 5-6% being reported. In addition, like other anxiety disorders, GAD also shows comorbidity with depression and ...

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Treatment of generalized anxiety disorder

Treatment of generalized anxiety disorder Anxiety disorders—generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), panic disorder (PD), post-traumatic stress disorder (PTSD), and social anxiety disorder (SAD)—are common, persistent, and cause substantial impairment. With lifetime prevalence estimates of over 25%, they constitute a group that is the most frequently occurring of...

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Treatment of Generalized Anxiety Disorder

Generalized anxiety disorder (GAD) is a common condition, with a lifetime prevalence of approximately 5% in the United States adult population according to the Epidemiological Catchment Area (ECA) study [1]. In comparison, Kendler et al [2] reported a lifetime prevalence of 3.6%. The National Comorbidity Survey reported a lifetime prevalence of 5.1% [3]. An international (World Health Organizat...

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Gabapentin is frequently used in the treatment of anxiety disorders. However, there are no randomized controlled trials on the effectiveness of this medication in generalized anxiety disorder (GAD), and there are only a few case reports. We present a case of a 59-year-old female with a psychiatric history of GAD. The patient discontinued benzodiazepines after more than 7 years of daily treatmen...

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Roemer and Orsillo (this issue) make a credible case for the integration of acceptance-based treatment techniques into cognitive-behavioral therapy (CBT) for generalized anxiety disorder (GAD). Only approximately 50% of GAD patients achieve clinically significant change with CBT (Chambless & Gillis, 1993), suggesting that additional treatment techniques need to be tested to improve response rat...

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ژورنال

عنوان ژورنال: The International Journal of Neuropsychopharmacology

سال: 2002

ISSN: 1461-1457,1469-5111

DOI: 10.1017/s1461145702003048